can you tell us what it means to have a purple line well above a brown line, meaning you have a line that actually shows positive versus a placebo? >> yeah, so the six-minute walk test is the primary outcome measure that is studied to understand the progression of ducenne must -- muscular dystrophy patients end up in a wheelchair. we measure their progression by this six-minute walk. we selected a population that we would have expected would have declined over 48 weeks. in fact, the placebo delayed treatment cohort that did decline through 36 weeks was something we expected. and that was a typical sign of this progressive disease. the fact that we showed a stabilization through 36 weeks excited the prospect of this drug. it excited the researchers and clinicians and the advocacy organizations in duchenne. now we've gone a step further. not only did we show stability through 48 weeks but we showed an improvement, as you mentioned. i'll also say the placebo drug is now on drug and they're producing the protein. so the best case scenario we were hoping for was a stabilization of the pro